China(Hongkong)
GDC-0994
- Min.Order: 5 Metric Ton
- Payment Terms:
- Product Details
Keywords
- GDC-0994
- ERK inhibitor
Quick Details
- ProName: GDC-0994
- Application: for R&D
- ProductionCapacity: Metric Ton/Day
- Purity: 99
- LimitNum: 5 Metric Ton
Superiority
First seller on the market, lowest price, highest quality
Details
GDC-0994 is a potent and selective Erk1/2 inhibitor.
An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
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